Drug Name

Triamterene (Triamterene/ Hydrochlorothiazide)

Drug Uses

Triamterene pill combines Triamterene as well as Hydrochlorothiazide. Triamterene ia potassium-conserving (antikaliuretic) diuretic with relatively weak natriuretic properties. Hydrochlorothiazide is a diuretic as well as antihypertensive agent. It blocks the renal tubular absorption of sodium as well as chloride ions.

How Taken

Take Triamterene as directed by your doctor.

• Take Triamterene by mouth with food.
• Incase you possess trouble swallowing the tablet whole, it may be crushed or chewed with a little water.

Ask your health care provider any questions you may possess about how to take Triamterene.

Drug Class as well as Mechanism

Triamterene is a potassium-conserving (antikaliuretic) diuretic with relatively weak natriuretic properties. It exerts its diuretic effect on the distal renal tubule to inhibit the reabsorption of sodium in exchange for potassium as well as hydrogen. With this action, triamterene increases sodium excretion as well as reduces the excessive loss of potassium as well as hydrogen associated with hydrochlorothiazide. Triamterene is not a competitive antagonist of the mineralocorticoids as well as its potassium-conserving effect is observed in patients with Addison's disease, i.e., without aldosterone. Triamterene's onset as well as duration of activity is similar to hydrochlorothiazide.

Hydrochlorothiazide is a diuretic as well as antihypertensive agent. It blocks the renal tubular absorption of sodium as well as chloride ions. This natriuresis as well as diuresis is accompanied by a secondary loss of potassium as well as bicarbonate. Onset of hydrochlorothiazide's diuretic effect occurs within two hours as well as the peak action takes place in four hours. Diuretic activity persists for approximately six to twelve hours.

Missed Dose

Incase you miss a dose of Triamterene as well as are using it regularly, take it as soon as likely. Incase it is almost time for your next dose, skip the missed dose as well as go back to your normal dosing schedule. Do not take 2 doses at once.

Storage

Store Triamterene at room temperature, between 68 as well as 77 degrees F (20 as well as 25 degrees C). Store away from heat, moisture, as well as light. Do not store in the bathroom. Keep in a close, light-resistant container. Keep Triamterene out of the reach of children as well as away from pets.

Warnings/Precautions

Do not take Triamterene if:

• you are allergic to any ingredient in Triamterene;
• you are using potassium supplements, another potassium-sparing diuretic (e.g., amiloride), or an aldosterone blocker (e.g., eplerenone);
• you are unable to urinate or possess high blood potassium levels or severely decreased liver or kidney function.

Contact your doctor or health care provider fair away incase any of these apply to you.

Important:

• Triamterene may cause dizziness. This effect may be worse incase you take it with alcohol or confident medicines. Take Triamterene with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Check with your doctor before you take a salt substitute or a product that has potassium in it.
• Tell your doctor or dentist that you take Triamterene before you receive any health examination or dental care, emergency care, or surgery.
• Lab tests, including blood electrolytes, blood cell counts, kidney as well as liver function tests, blood uric acid levels, as well as blood pressure, may be performed while you take Triamterene. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor as well as lab appointments.
• Take Triamterene with caution in the elderly; they may be more sensitive to its effects.
• Triamterene should not be used in children; safety as well as effectiveness in children possess not been confirmed.
• Pregnancy as well as breast-feeding: It is not known incase Triamterene can cause harm to the fetus. Incase you become pregnant, contact your doctor. You will need to discuss the benefits as well as risks of using Triamterene while you are pregnant. It is not known incase Triamterene is found in breast milk. Do not breast-feed while using this medicine.

Likely Side Effects

Check with your doctor incase any of these most ordinary side effects persist or become bothersome:

• diarrhea; headache; loss of appetite; nausea; weakness.

Seek health examination attention fair away incase any of these very bad side effects occur:

• very bad allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); moistureless mouth; excessive thirst; unhurried or irregular heart rate; unusual muscle weakness; unusual tiredness; vomiting; yellowing of the skin or eyes.

More Information

Triamterene is to be used only by the patient for whom it is prescribed. Do not share it with other people.

Incase your symptoms do not improve or incase they become worse, check with your doctor.