Drug Name

Duetact (Glimepiride/Pioglitazone)

Drug Uses

Duetact is used for treating type 2 diabetes in confident patients. It is used along with diet as well as exercise.

How Taken

Take Duetact as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Duetact . Talk to your pharmacist incase you possess questions about this information.

Take Duetact by mouth with breakfast or the earliest main meal of the day unless instructed otherwise by your doctor. Continue to take Duetact even incase you feel well. Do not miss any doses.

Taking Duetact at the alike time each day will help you remember to take it.

Drug Class as well as Mechanism

Duetact is a thiazolidinedione as well as sulfonylurea antidiabetic combination. It lowers blood sugar by making the cells of the body more sensitive to the action of insulin. It as well as causes the pancreas to release insulin, which helps to lower blood sugar.

Missed Dose

Incase you miss a dose of Duetact , take it as soon as likely. Incase it is almost time for your next dose, skip the missed dose as well as go back to your normal dosing schedule. Do not take 2 doses at once.

Storage

Store Duetact at room temperature, between 68 as well as 77 degrees F (20 as well as 25 degrees C). Store away from heat, moisture, as well as light. Do not store in the bathroom. Keep in a close, light-resistant container. Keep Duetact out of the reach of children as well as away from pets.

Warnings/Precautions

Do NOT take Duetact if:

• you are allergic to any ingredient in Duetact
• you possess moderate to very bad heart failure, liver problems or abnormal liver function tests, confident very bad problems associated with diabetes (eg, diabetic ketoacidosis, diabetic coma), moderate to very bad burns, or very high blood acid levels (acidosis)
• you possess type 1 diabetes
• you are using bosentan

Contact your doctor or health care provider fair away incase any of these apply to you.

Some health examination conditions may work with Duetact . Tell your doctor or pharmacist incase you possess any health examination conditions, especially incase any of the following apply to you:

• incase you are pregnant, planning to become pregnant, or are breast-feeding
• incase you are using any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• incase you possess allergies to medicines, foods, or other substances
• incase you possess had a very bad allergic reaction (eg, very bad rash, hives, breathing difficulties, dizziness) to any other sulfonamide medicine such as acetazolamide, celecoxib, confident diuretics (eg, hydrochlorothiazide), glipizide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide
• incase you possess a history of kidney, thyroid, heart, or blood vessel problems; stroke; confident hormonal problems (eg, adrenal or pituitary problems, syndrome of inappropriate secretion of antidiuretic hormone [SIADH]); or abridged blood sodium levels
• incase you possess stomach or bowel problems (eg, stomach or bowel blockage, stomach paralysis), drink alcohol, or possess had without money nutrition
• incase you possess very without money health, a high fever, a very bad infection, very bad diarrhea, or high blood acid levels, or incase you possess had a very bad injury
• incase you possess swelling problems (edema) or confident eye problems (macular edema)
• incase you will be having surgery

Some MEDICINES MAY WORK with Duetact . Tell your health care provider incase you are using any other medicines, especially any of the following:

• Bosentan because liver problems may occur, as well as the effectiveness of both medicines may be decreased
• Beta-blockers (eg, propranolol) because the risk of abridged blood sugar may be increased. They may as well as hide confident signs of abridged blood sugar as well as make it more difficult to notice
• Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), azole antifungals (eg, miconazole, ketoconazole), chloramphenicol, clofibrate, fenfluramine, insulin, metformin, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), phenylbutazone, probenecid, quinolone antibiotics (eg, ciprofloxacin), salicylates (eg, aspirin), as well as sulfonamides (eg, sulfamethoxazole) because the risk of abridged blood sugar may be increased
• Calcium channel blockers (eg, diltiazem), corticosteroids (eg, prednisone), decongestants (eg, pseudoephedrine), diazoxide, diuretics (eg, furosemide, hydrochlorothiazide), estrogens, hormonal contraceptives (eg, birth control pills), isoniazid, niacin, phenothiazines (eg, promethazine), phenytoin, rifamycins (eg, rifampin), sympathomimetics (eg, albuterol, epinephrine), or thyroid supplements (eg, levothyroxine) because they may decrease Duetact 's effectiveness, resulting in high blood sugar
• Gemfibrozil because blood sugar may be increased or decreased
• Anticoagulants (eg, warfarin) because their effectiveness may be decreased or the risk of their side effects may be increased by Duetact

Likely Side Effects

All medicines may cause side effects, but many people possess no, or minor, side effects. Check with your doctor incase any of these most ORDINARY side effects persist or become bothersome:

• Diarrhea; headache; limb pain; muscle aches; nausea; upper respiratory tract infection; weight gain.

Seek health examination attention fair away incase any of these VERY BAD side effects occur:

• Very bad allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; chest pain; confusion; fever, chills, or sore throat; increased or painful urination; irregular heartbeat; symptoms of heart failure (eg, shortness of breath; unexpected unexplained weight gain; swelling of the hands, ankles, or feet); symptoms of liver problems (eg, not light urine, very bad or persistent nausea, stomach pain, unexplained vomiting or loss of appetite, yellowing of the skin or eyes); symptoms of abridged blood sugar (eg, anxiety, chills, dizziness or drowsiness, headache, increased hunger, increased sweating, tremors); unusual bone pain; unusual bruising or bleeding; unusual tiredness or weakness.

More Information

Incase you possess any questions about Duetact , please talk with your doctor, pharmacist, or other health care provider.

Duetact is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or incase they become worse, check with your doctor.