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2nd Generation Antidepressants Prove Effective
2nd Generation Antidepressants Prove EffectiveTUESDAY, Nov. 18 (HealthDay News) -- Subordinate generation antidepressants are all equally effective, according to a recent clinical practice guideline released by the American College of Physicians. The guideline authors reviewed more than 200 published studies about the benefits as well as risks of the following subordinate generation drugs: bupropion, citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, mirtazapine, nefazodone, paroxetine, sertraline, trazadone as well as venlafaxine.
"The studies we analyzed show that subordinate generation drugs possess dissimilar adverse effects but are equally effective for treating depression," lead author Dr. Amir Qaseem, senior health examination associate in ACP's Clinical Programs as well as Quality of Care Department, said in a group news release. "ACP recommends that physicians make treatment decisions based on side effects, cost, as well as patient preferences, as well as make essential changes in therapy incase the response is not sufficient after six to eight weeks. Doctors should as well as assess patient status as well as adverse effects on a normal basis starting within one to two weeks of starting the treatment." The guideline as well as recommends that doctors continue treatment for four to nine months after a satisfactory response to an antidepressant in patients with a earliest episode of major depression. A longer course of treatment may help halt relapse or recurrence in patients who've had two or more episodes of depression. The guideline was published Nov. 18 in the journal Annals of Internal Medicine. Depression, which will affect about 16% of American adults at some point in their lives, can be triggered by stressful situations such as the loss of a job or death of a loved one. Depression treatment options include drugs, psychotherapy, as well as cognitive behavioral therapy. In drug therapy, subordinate generation antidepressants are often used, because they're effective as well as possess fewer side effects than older antidepressants. -- Robert Preidt SOURCE: American College of Physicians, news release, Nov. 18, 2008
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